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Issue: Vol. 22: 30 Nov. 2022
Type: Proceedings Papers
Published: 2022-11-30
DOI: 10.11646/zoosymposia.22.1.195
Page range: 313
Abstract views: 115
PDF downloaded: 10

Chromosome-level genomic assembly and allergome inference reveal novel allergens in the storage mite, Tyrophagus putrescentiae

Department of Pediatrics Laboratory, The Affiliated Wuxi Children’s Hospital of Nanjing Medical University, Wuxi 214023, China
Department of Biological Sciences, Purdue University, IN 47907, USA
Department of Respiratory, The Affiliated Wuxi Children’s Hospital of Nanjing Medical University, Wuxi 214023, China
Department of Respiratory, The Affiliated Wuxi Children’s Hospital of Nanjing Medical University, Wuxi 214023, China
Department of General Medicine, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Clinical Research Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Clinical Research Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Clinical Research Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Clinical Research Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Clinical Research Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi 214023, China
Tyrophagus putrescentiae storage mite allergen genome allergome

Abstract

Tyrophagus putrescentiae is a common storage mite in house dust, stored grains and other food. It has been demonstrated as an important indoor allergen source resulting in IgE-mediated responses and allergic diseases in genetically predisposed patients. Identification and characterization of its allergens using whole genome sequencing is needed for improving allergy diagnostics and developing better immunotherapeutic vaccines.

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